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Medical

Severe allergic reaction (anaphylaxis)

Trouble breathing, swollen lips or tongue, hives all over the body.

Call 911
Do this nowTap each step when done
  1. 1Call 911 or have someone call while you act.
  2. 2Use their epinephrine auto-injector. Follow the printed instructions.
  3. 3Inject it into the outer thigh. It can go through clothing.
  4. 4Hold it in place for the time the manufacturer indicates, and massage.
  5. 5Lay them down with legs raised. Half-sitting if they have trouble breathing.
  6. 6Always go to the hospital, even if they improve. It can come back hours later.
1. Firm fist; thumb away from the ends   2. Outer part of the thigh, at a right angle   3. Hold for the time indicated and massage   4. Lying down, legs raised
Don't
  • Don't put your thumb over either end.
  • Don't stand them up or make them walk.
  • Don't wait for them to get worse before using the auto-injector.
Have ready
  • Two prescribed auto-injectors, always in the same place.
  • One in the 72-hour backpack.
  • Over-the-counter antihistamine for mild reactions.
  • Check the expiration date. Don't leave them in the car.
Key factIf they don't improve, they may need a second dose according to their medical plan and 911. Give the used auto-injector to the paramedics.

More detail

Ch. 7 · First aidOpen chapter
Next urgent cardUnconscious person / not breathing: CPR and AED

Reviewed: Nov 2026 · Sources: Chapter 7 · First Aid